Reigner, Bruno: search on Z-Library

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1

Estimating the starting dose for entry into humans: principles and practice

Bruno G. Reigner, Karen Blesch

Journal:

European Journal of Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 158 KB

english, 2002

2

Prediction of Hepatic Metabolic Clearance Based on Interspecies Allometric Scaling Techniques andIn Vitro-In VivoCorrelations

Dr Thierry Lavé, Philippe Coassolo, Bruno Reigner

Journal:

Clinical Pharmacokinetics

Year:

1999

Language:

english

File:

PDF, 277 KB

english, 1999

3

Saturable rate of cefatrizine absorption after oral administration to humans

Bruno G. Reigner, William Couet, Jean-Paul Guedes, Jean-Bernard Fourtillan, Thomas N. Tozer

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1990

Language:

english

File:

PDF, 883 KB

english, 1990

4

Pediatric Dosing of Ganciclovir and Valganciclovir: How Model-based Simulations Can Prevent Underexposure and Potential Treatment Failure

Jorga, Karin, Reigner, Bruno, Chavanne, Clarisse, Alvaro, Giuseppe, Frey, Nicolas

Journal:

CPT: Pharmacometrics & Systems Pharmacology

Year:

2018

Language:

english

File:

PDF, 850 KB

english, 2018

5

Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

Johannes Schüller, Jim Cassidy, Etienne Dumont, Brigitte Roos, Sarah Durston, Ludger Banken, Masahiro Utoh, Kazushige Mori, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 106 KB

english, 2000

6

Pharmacokinetic and Pharmacodynamic Properties of Methoxy Polyethylene Glycol-Epoetin Beta Are Unaffected by the Site of Subcutaneous Administration 1

Fishbane, Steven, Pannier, Anne, Liogier, Xavier, Jordan, Paul, Dougherty, Frank C., Reigner, Bruno

Journal:

Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

7

Clinical Pharmacokinetics of Capecitabine

Dr Bruno Reigner, Karen Blesch, Erhard Weidekamm

Journal:

Clinical Pharmacokinetics

Year:

2001

Language:

english

File:

PDF, 253 KB

english, 2001

8

Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients

Christopher Poole, Jill Gardiner, Chris Twelves, Patrick Johnston, Peter Harper, Jim Cassidy, Jayne Monkhouse, Ludger Banken, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

9

Influence of the antacid Maalox on the pharmacokinetics of capecitabine in cancer patients

Bruno Reigner, Saly Clive, Jim Cassidy, Duncan Jodrell, Rainer Schulz, Timothy Goggin, Ludger Banken, Brigitte Roos, Masahiro Utoh, Thomas Mulligan, Erhard Weidekamm

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 114 KB

english, 1999

10

Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients

Jim Cassidy, Chris Twelves, David Cameron, William Steward, Ken O'Byrne, Duncan Jodrell, Ludger Banken, Timothy Goggin, David Jones, Brigitte Roos, Erine Bush, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

11

Population Pharmacokinetic/Pharmacodynamic Model for C.E.R.A. in Both ESA-Naïve and ESA-Treated Chronic Kidney Disease Patients With Renal Anemia

Chanu, Pascal, Gieschke, Ronald, Charoin, Jean-Eric, Pannier, Anne, Reigner, Bruno

Journal:

Journal of Clinical Pharmacology

Year:

2010

Language:

english

File:

PDF, 558 KB

english, 2010

12

Effect of hemodialysis and hemofiltration on plasma C.E.R.A. concentrations

John K. Leypoldt, Mahmoud Loghman-Adham, Paul Jordan, Bruno Reigner

Journal:

Hemodialysis International

Year:

2012

Language:

english

File:

PDF, 459 KB

english, 2012

13

The effect of severe hepatic impairment on the pharmacokinetics and haematological response of C.E.R.A.

Kupčová, Viera, Šperl, Jan, Pannier, Anne, Jordan, Paul, Dougherty, Frank C., Reigner, Bruno

Journal:

Current Medical Research and Opinion

Year:

2008

Language:

english

File:

PDF, 228 KB

english, 2008

14

Simultaneous assay of pentachlorophenol and its metabolite, tetrachlorohydroquinone, by gas chromatography without derivatization

Bruno G. Reigner, Jean F. Rigod, Thomas N. Tozer

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1990

Language:

english

File:

PDF, 926 KB

english, 1990

15

Transthoracic Endoscopy for Upper Thoracic Chemical Sympathectomy

Eustathios Bardaxoglou, Bruno Reigner, Bernard Enon, Nicolas Tolstuchow, François Lescalié, Michel Peret, Jean-Michel Chevalier

Journal:

Annals of Vascular Surgery

Year:

1992

Language:

english

File:

PDF, 266 KB

english, 1992

16

Pharmacokinetics of capecitabine (Xeloda) in Japanese and Caucasian patients with breast cancer

Bruno Reigner, Toru Watanabe, Johannes Schüller, Helen Lucraft, Yasutsuna Sasaki, John Bridgewater, Toshiaki Saeki, James McAleer, Masaru Kuranami, Christopher Poole, Mitsunori Kimura, Jayne Monkhouse

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2003

Language:

english

File:

PDF, 243 KB

english, 2003

17

Subcutaneous injection pain with C.E.R.A., a continuous erythropoietin receptor activator, compared with darbepoetin alfa

Pannier, Anne, Jordan, Paul, Dougherty, Frank C., Bour, Fabrice, Reigner, Bruno

Journal:

Current Medical Research and Opinion

Year:

2007

Language:

english

File:

PDF, 270 KB

english, 2007

18

Theoretical model for both saturable rate and extent of absorption: Simulations of cefatrizine data

William R. Couet, Bruno G. Reigner, Jean-Paul Guedes, Thomas N. Tozer

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 516 KB

english, 1991

19

Model‐based approach for methoxy polyethylene glycol‐epoetin beta drug development in paediatric patients with anaemia of chronic kidney disease [142/999 characters (incl. spaces)]

Chanu, Pascal, Schaefer, Franz, Warady, Bradley A., Schmitt, Claus Peter, Reigner, Bruno, Schnetzler, Gabriel, Meyer Reigner, Sylvie, Eisner, Mark, Weichert, Arlette, Frey, Nicolas

Journal:

British Journal of Clinical Pharmacology

Year:

2019

File:

PDF, 1.04 MB

2019

20

Disposition, Bioavailability, and Serum Protein Binding of Pentachlorophenol in the B6C3F1 Mouse

Bruno G. Reigner, Jean F. Rigod, Thomas N. Tozer

Journal:

Pharmaceutical Research

Year:

1992

File:

PDF, 905 KB

1992

21

Pharmacokinetic concepts in assessing intake of pentachlorophenol by rats after exposure through drinking water

Bruno G. Reigner, Ramon A. Gungon, Frederic Y. Bois, Lauren Zeise, Thomas N. Tozer

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 616 KB

english, 1992

22

C.E.R.A.: pharmacodynamics, pharmacokinetics and efficacy in patients with chronic kidney disease

Locatelli, Francesco, Reigner, Bruno

Journal:

Expert Opinion on Investigational Drugs

Year:

2007

Language:

english

File:

PDF, 218 KB

english, 2007

23

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

Yeung, Wai Yin, Whitehead, John, Reigner, Bruno, Beyer, Ulrich, Diack, Cheikh, Jaki, Thomas

Journal:

Pharmaceutical Statistics

Year:

2015

Language:

english

File:

PDF, 775 KB

english, 2015

24

A human capecitabine excretion balance and pharmacokinetic study after administration of a single oral dose of 14C-labelled drug

Ian R. Judson, Philip J. Beale, José M. Trigo, Wynne Aherne, Thomas Crompton, David Jones, Ernie Bush, Bruno Reigner

Journal:

Investigational New Drugs

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

25

An Evaluation of the Integration of Pharmacokinetic and Pharmacodynamic Principles in Clinical Drug Development

Dr Bruno G. Reigner, Peter E. O. Williams, Indra H. Patel, Jean-Louis Steimer, Carl Peck, Peter van Brummelen

Journal:

Clinical Pharmacokinetics

Year:

1997

Language:

english

File:

PDF, 1.06 MB

english, 1997

26

Population pharmacokinetics and concentration–effect relationships of capecitabine metabolites in colorectal cancer patients

Ronald Gieschke, Hans-Ulrich Burger, Bruno Reigner, Karen S. Blesch, Jean-Louis Steimer

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

27

Bayesian adaptive dose-escalation designs for simultaneously estimating the optimal and maximum safe dose based on safety and efficacy

Yeung, Wai Yin, Reigner, Bruno, Beyer, Ulrich, Diack, Cheikh, Sabanés bové, Daniel, Palermo, Giuseppe, Jaki, Thomas

Journal:

Pharmaceutical Statistics

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

28

Bayesian adaptive designs in single ascending dose trials in healthy volunteers

Guédé, David, Reigner, Bruno, Vandenhende, Francois, Derks, Mike, Beyer, Ulrich, Jordan, Paul, Worth, Eric, Diack, Cheikh, Frey, Nicolas, Peck, Richard

Journal:

British Journal of Clinical Pharmacology

Year:

2014

Language:

english

File:

PDF, 1003 KB

english, 2014

29

In Situ Thrombolysis for Late Occlusion of Suprafemoral Prosthetic Grafts

Bernard Enon, Bruno Reigner, François Lescalié, Philippe l'Hoste, Michel Peret, Jean-Michel Chevalier

Journal:

Annals of Vascular Surgery

Year:

1993

Language:

english

File:

PDF, 471 KB

english, 1993

30

Phase I and Pharmacokinetic Study of the Oral Fluoropyrimidine Capecitabine in Combination With Paclitaxel in Patients With Advanced Solid Malignancies

Villalona-Calero, Miguel A., Weiss, Geoffrey R., Burris, Howard A., Kraynak, Maura, Rodrigues, Gladys, Drengler, Ronald L., Eckhardt, S. Gail, Reigner, Bruno, Moczygemba, Judy, Burger, Hans Ulrich, Gr

Journal:

Journal of Clinical Oncology

Year:

1999

Language:

english

File:

PDF, 92 KB

english, 1999

31

Eversion Endarterectomy of the Internal Carotid Artery: Midterm Results of a New Technique

Bruno Reigner, Philippe Reveilleau, Muriel Gayral, Xavier Papon, Bernard Enon, Jean-Michel Chevalier

Journal:

Annals of Vascular Surgery

Year:

1995

Language:

english

File:

PDF, 458 KB

english, 1995

32

Development of a PBPK Model for Mefloquine and its Application alongside a Clinical Effectiveness Model to Select an Optimal Dose for Prevention of Malaria in Young Caucasian Children

Johnson, Trevor N., Cleary, Yumi, Parrott, Neil, Reigner, Bruno, Smith, James R., Toovey, Stephen

Journal:

British Journal of Clinical Pharmacology

Year:

2018

Language:

english

File:

PDF, 814 KB

english, 2018

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